甘建华

发布时间:2021-05-18浏览次数🏸:8089

Structures and implications of the C962R protein of African swine fever virusNucleic Acids Res, 51(17): 9475-9490 (2023)

  • H. Liu, Y. Gao, J. Mathivanan, Z. Armour-Garb, Z. Shao, Y. Zhang, X. Zhao, Q. Shao, W. Zhang, J. Yang, C. Cao, H. Li, J. Sheng*, J. Gan*, “Crystal structures and identification of novel Cd2+-specific DNA aptamer”Nucleic Acids Res, 51(9): 4625-4636 (2023)

  • Z. Shao, J. Yang, Y. Gao, Y. Zhang, X. Zhao, Q. Shao, W. Zhang, C. Cao, H. Liu, J. Gan*, Structural and functional studies of PCNA from African swine fever virus.J. Virol, 97(8): e0074823 (2023)

  • Y. Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase PNat Commun. 13(1):2290 (2022)

  • Y. Zhang, Z. Shao, Y. Gao, B. Fan, J. Yang, X. Chen, X. Zhao, Q. Shao, W. Zhang, C. Cao, H. Liu, J. Gan*Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein”, Comput Struct Biotec J, 20: 4645-4655 (2022)

  • B. WangQ. LuoY. LiK. DuZ. WuT. LiW. ShenC. Huang*, J. Gan*A. Dong*, “Structural insights into partner selection for MYB and bHLH transcription factor complexes” Nat Plants, 8(9): 1108-1117 (2022)

  • R. CuiH. LiJ. ZhaoX. LiJ. Gan*J. Ma*, Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1Nucleic Acids Res, 50(17): 10169-10186 (2022)

  • Y. Xu, J. Yang, W. Li, S. Song, Y. S, L. Wu, J. Sun, Me. Hou, J. Wang, X. Jia, H. Zhang, M. Huang, T. Lu, J. Gan*, Y. Feng*, “Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target” Plos Pathog, 18(7): e1010615 (2022)

  • G. Cui, Y. Zhang, X. Xu, Y. Liu, Z. Li, M. Wu, J. Liu*, J. Gan*, H. Liang*, PmiR senses 2-methylisocitrate levels to regulate bacterial virulence in Pseudomonas aeruginosa” Sci Adv, 8(49): eadd4220 (2022)

  • Y. Gao, H. Liu, C. Zhang, S. Su, Y. Chen, X. Chen, Y. Li, Z. Shao, Y. Zhang, Q. Shao, J. Li, Z. Huang, J. Ma, J. Gan*, “Structural basis for guide RNA trimming by RNase D ribonuclease in Trypanosoma brucei”, Nucleic Acids Res. 49(1): 568-583 (2021)

  • H. Jiang, Y. Gao, L. Zhang, D. Chen*, J. Gan*, A. Murchie*,“The identification and characterization of a selected SAM-dependent methyltransferase ribozyme that is present in natural sequences” Nat Catal, 4: 872-881 (2021)

  • X. Chen, S. Su, Y. Chen, Y. Gao, Y. Li, Z. Shao, Y. Zhang, Q. Shao, H. Liu, J. Li, J. Ma, J. Gan*, “Structural studies reveal a ring-shaped architecture of deep-sea vent”, Nucleic Acids Res. 48(6): 3343-3355 (2020)

  • Y. Chen, X. Chen, Q. Huang, Z. Shao, Y. Gao, Y. Li, C. Yang, H. Liu, J. Li, Q. Wang, J. Ma, Y. Zhang*, Y, Gu*, J. Gan*, “A unique DNA-binding mode of African Swine fever virus AP endonuclease”, Cell Discov, 6:13 (2020)

  • Zhang, H. Zhang, X. Xu, Y. Wang, W. Chen, Y. Wang, Z. Wu, N. Tang, Y. Wang, S. Zhao, J. Gan*, Q. Ji*, “Catalytic-state structure and engineering of Streptococcus thermophiles Cas9”, Nat Catal, 3: 813-823 (2020)

  • B. Wang, Q. Luo,Y. Li, L. Yin, N. Zhou, X Li, J. Gan*, A. Dong*, “Structural insights into target DNA recognition by R2R3-MYB transcription factors” Nucleic Acids Res. 48 (1): 460-471 (2020)

  • Y. Chen, H. Liu, C. Yang, Y. Gao, X. Yu, X. Chen, R. Cui, L. Zheng, S. Li, X. Li, J. Ma, Z. Huang*, J. Li*, J. Gan*, “Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues”, Nature Commun. 10(1):387 (2019)

  • Qian, H. Yu, P. Li, E. Zhu, Q. Yao, C. Tai, Z. Deng, K. Gerdes, X. He*, J. Gan*, H. Ou*, “Toxin-antitoxin operon kacAT of Klebsiella pneumoniae is regulated by conditional cooperativity via a W-shaped KacA-KacT complex”, Nucleic Acids Res. 47(14): 7690-7702 (2019)

  • W. Chen, H. Zhang, Y. Zhang, Y. Wang, J. Gan*, Q. Ji*, “Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease” PloS Biol 17(10):e3000496 (2019)

  • H. Liu, R. Wang, X. Yu, F. Shen, W. Lan, P. Haruehanroengra, Q. Yao, J. Zhang, Y. Chen, S. Li, B. Wu, L. Zheng, J. Ma, J. Lin, C. Cao*, J. Li*, J. Sheng*, J. Gan*, “High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads”, Nucleic Acids Res. 46(21): 11627-11638 (2018)

  • C. Yang, R. Wu, H. Liu, Y. Chen, Y. Gao, X. Chen, Y. Li, J. Ma, J. Li*, J. Gan*, “Structural insights into DNA degradation by human mitochondrial nuclease MGME1”, Nucleic Acids Res. 46(20): 11075-11088 (2018)

  • H. Liu#, X. Yu#, Y. Chen, J. Zhang, B. Wu, L. Zheng, P. Haruehanroengra, R. Wang, S. Li, J. Lin, J. Li, J. Sheng, Z. Huang*, J. Ma*, J. Gan*, “Crystal structure of an RNA-cleaving DNAzyme”, Nat Commun. 8(1): 2006 (2017)

  • H. Liu, F. Shen, P. Haruehanroengra, Q. Yao, Y. Cheng, Y. Chen, C. Yang, J. Zhang, B. Wu, Q. Luo, R. Cui, J. Li, J. Ma*, J. Sheng*, J. Gan*, “A DNA structure containing AgI-mediated G:G and C:C base pairs”, Angew Chem Int Ed Engl. 56(32):9430-9434 (2017)

  • H. Liu#, C. Chen#, P. Haruehanroengra, Q. Yao, Y. Chen, C. Yang, Q. Luo, B. Wu, J. Li, J. Ma*, J. Sheng*, J. Gan*, “Flexibility and stabilization of HgII-mediated C:T and T:T base pairs in DNA duplex”, Nucleic Acids Res, 45(5):2910-2918 (2017)

  • F. Shen, Z. Luo, H. Liu, R. Wang, S. Zhang, J. Gan*, J. Sheng*, “Structural insights into RNA duplexes with multipile 2’-5’-linkages”, Nucleic Acids Res. 45(6):3537-3546 (2017)

  • Y. Chen, J. Zhang, H. Liu, Y. Gao, X. Li, L. Zheng, R. Cui, Q. Yao, L. Rong, J. Li, Z. Huang*, J. Ma*, J. Gan*, “Unique 5’-P recognition and basis for dG:dGTP misincorporation of ASFV DNA polymerase X”, PloS Biol 15(2):e1002599 (2017)

  • J. Zhang, H. Liu, Q. Yao, X. Yu, Y. Chen, R. Cui, B. Wu, L. Zheng, J. Zuo, Z. Huang*, J. Ma*, J. Gan*, “Structural basis for single-stranded RNA recognition and cleavage by C3PO”, Nucleic Acids Res, 44(19):9494-9504 (2016)

  • J. Zhao#, X. Yu#, M. Zhu, H. Kang, J. Ma, M. Wu, J. Gan*, X. Deng*, H. Liang*, Structural and molecular mechanism of CdpR involved in quorum-sensing and bacterial virulence in Pseudomonas aeruginosa, PloS Biol, 14(4):e1002449 (2016).

  • J. Gan, J. Tropea, B. Austin, D. Court, D. Waugh, X. Ji*, “Structural Insight into the Mechanism of Double-Stranded RNA Processing by Ribonuclease III” Cell, 124(2): 355–366 (2006)



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